Scientists Just Discovered A New Biggest Human Organ – The Interstitium

A group of scientists has discovered a new biggest human organ. It is known as the interstitium. This discovery made a need for an upgrade in the books of human anatomy.

The human body was thought to have 79 organs until the point that analysts unearthed a peculiar wonder and found this 80th organ of the human body.

As reported according to the data published in Science Journal, an organ has been identified by scientists which might be the “biggest organ” in the human body, named as the interstitium. This was earlier thought to be widespread, fluid-filled spaces within and between tissues all over the body.


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Scientists reported the body contains a previously undiscovered network of fluid-filled pockets and collagen underneath the skin which is also made up of a thick and compact layer of connective tissue that covers most of the body and internal organs spreading throughout the whole body. They identified it for the first time observing this living tissues at a high microscopic scale reporting this structure to be considered as an organ itself.

A co-senior author of the study and the professor of pathology at NYU Langone Health in New York, Dr. Neil Theise said,

Initially, we were just thinking it’s an interesting tissue, but when you actually delve into how people define organs, it sort of runs around one or two ideas: that it has a unitary structure or that it’s a tissue with a unitary structure, or it’s a tissue with a unitary function. This has both. This structure is the same wherever you look at it, and so are the functions that we’re starting to elucidate.

The study’s other authors said,

This organ is apreviously unappreciated fluid-filled interstitial space, draining to lymph nodes and supported by a complex network of thick collagen bundles.


★ How interstitium was discovered?

Scientists came across this organ during endoscopies. Endoscopy is a non-surgical method in which specialists utilize a little camera joined to a tube to look at the gastrointestinal tract. Living human tissue pictures could be seen after sensors broke down the subsequent fluorescent examples, analyzing the resulting patterns to diagnose the diseases.

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As a result, Dr. Neil Theise said in Journal statement,

This fixation artifact of collapse has made a fluid-filled tissue type throughout the body appear solid in biopsy slides for decades, and our results correct for this to expand the anatomy of most tissues. This finding has potential to drive dramatic advances in medicine, including the possibility that the direct sampling of interstitial fluid may become a powerful diagnostic tool.


★ What interstitium was considered earlier?

Earlier, scientists thought these tissue layers were a thick divider of collagen, which the principle auxiliary protein found in skin and other connective tissues. Be that as it may, the new finding uncovered this tissue is more similar to an open, liquid-filled passageway, supported by a cross-section of thick collagen fiber groups.


★ A little about the interstitium anatomy.

The examination demonstrates that the new human organ is really a system of compartments loaded with fluid. As indicated by specialists, these interstitial spaces are sorted out by a collagen work and can shrivel and extend and may in this manner fill in as safeguards.

Scientists additionally say that interstitium spaces may assume a critical part in helping malignant bodies spread to various parts of the body making it metastatic. In medical term, metastasis is the common term for a disease that spreads to an alternate piece of the body from where it began.

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At the point when malignancy or in other words cancer enters this layer, in the skin or via. the internal organs, it is then that it begins spreading to different parts of the body. In other words, the interstitium spaces make it easy for the spread of cancer throughout the body.


★ It’s future contribution to medical science and technology.

1. Interstitium could significantly advance the understanding of cancer and many other diseases.

2. These anatomic structures may be important in cancer metastasis, edema, fibrosis and mechanical functioning of many or all tissues and organs.

3. It will be helpful in the novel expansion and specification of the concept of the human body functioning in medical diagnosis and treatments.

4. It would change how we understood everything from acupuncture to inflammation forwarding into much detailed information in the near future.

5. This new organ could explain many of modern medicine’s mysteries which remained unexplored and unexplainable by other phenomena till date.

6. It will prioritize the reexamination of huge numbers of the normal functional exercises of various organs and of scattered liquid flow in the setting of ailments and various diseases.


This finding can possibly drive sensational advances in solution, including the likelihood that the immediate testing of interstitial liquid may turn into a capable indicative device and diagnostic tool.

Ronit Dey

Written by Ronit Dey

A blogger by passion with love for reading and writing. Am here at BlogPoke, to bring the best content updated daily to you.